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Structural characteristics of anabolic androgenic steroids contributing to binding to the androgen receptor and to their anabolic and androgenic activitiesare determined by its physical and chemical characteristics.Structure-activity relationship (SAR) tests, which are used widely for drug screening, are used to determine whether an anabolic drug or androgenic steroid is anabolical. SAR tests have shown that ascorbic acid and tadalafil are both anabolical. Anandamide is also an anabolic, but with slightly different structural characteristics. This report reviews the data on the structural characteristics that have contributed to and interactions between androgens, and the androgen receptor and its interactions with the anabolic and orrogenic anabolic steroids. There is still a great deal we do not know about the specific structural characteristics of anabolic and androgenic steroids, which may be related to their anabolic androgenic activities.Similar articles: